| The Life Ahead | 2020 | Madame Rosa | Movie |
| Human Voice | 2014 | Angela | Short Film |
| My House Is Full of Mirrors | 2010 | Romilda Villani | TV Movie |
| Nine | 2009 | Mamma | Movie |
| Too Much Romance… It's Time for Stuffed Peppers | 2004 | Maria (as Sofia Loren) | Movie |
| Lives of the Saints | 2004 | Teresa Innocente | TV Movie |
| Between Strangers | 2002 | Olivia | Movie |
| Francesca and Nunziata | 2001 | Francesca Montorsi | TV Movie |
| Soleil | 1997 | Maman Lévy | Movie |
| Grumpier Old Men | 1995 | Maria Sophia Coletta Ragetti | Movie |
| Ready to Wear | 1994 | Isabella de la Fontaine | Movie |
| Saturday, Sunday and Monday | 1990 | Rosa Priore | Movie |
| Running Away | 1989 | Cesira | TV Movie |
| The Fortunate Pilgrim | 1988 | Lucia | TV Show |
| Courage | 1986 | Marianna Miraldo | TV Movie |
| Qualcosa di biondo | 1984 | Aurora | TV Movie |
| Sophia Loren: Her Own Story | 1980 | Romilda Villani, Sophia | TV Movie |
| Firepower | 1979 | Adele Tasca | Movie |
| Angela | 1978 | Angela Kincaid | Movie |
| Blood Feud | 1978 | Titina Paterno | Movie |
| Brass Target | 1978 | Mara | Movie |
| A Special Day | 1977 | Antonietta Taberi | Movie |
| The Cassandra Crossing | 1976 | Jennifer Rispoli Chamberlain | Movie |
| La pupa del gangster | 1975 | Pupa | Movie |
| The Voyage | 1974 | Adriana De Mauro | Movie |
| Verdict | 1974 | Teresa Leoni | Movie |
| Brief Encounter | 1974 | Anna Jesson | TV Movie |
| Bianco, rosso e… | 1972 | Suor Germana | Movie |
| Man of La Mancha | 1972 | Aldonza, Dulcinea | Movie |
| Lady Liberty | 1971 | Maddalena Ciarrapico | Movie |
| The Priest's Wife | 1971 | Valeria Billi | Movie |
| Mera Naam Joker | 1970 | Self : picture on cover of Life Magazine (uncredited) | Movie |
| Sunflower | 1970 | Giovanna | Movie |
| Romeo und Julia '70 | 1969 | Sophia Loren (1969) | TV Show |
| Ghosts – Italian Style | 1968 | Maria Lojacono | Movie |
| A Countess from Hong Kong | 1967 | Natascha | Movie |
| More Than a Miracle | 1967 | Isabella Candeloro | Movie |
| Arabesque | 1966 | Yasmin Azir | Movie |
| Judith | 1966 | Judith Auerbach | Movie |
| Lady L | 1965 | Lady L, Lady Louise Lendale | Movie |
| Operation Crossbow | 1965 | Nora Van Ostamgen | Movie |
| Marriage Italian Style | 1964 | Filumena Marturano | Movie |
| The Fall of the Roman Empire | 1964 | Lucilla | Movie |
| Yesterday, Today and Tomorrow | 1963 | Adelina Sbaratti, Anna Molteni, Mara | Movie |
| Boccaccio '70 | 1962 | Zoe (segment “La riffa”) | Movie |
| Five Miles to Midnight | 1962 | Lisa Macklin | Movie |
| The Condemned of Altona | 1962 | Johanna von Gerlach | Movie |
| El Cid | 1961 | Jimena | Movie |
| Madame | 1961 | Catherine Hubscher, dite “Madame Sans-Gêne” | Movie |
| A Breath of Scandal | 1960 | Princess Olympia | Movie |
| Heller in Pink Tights | 1960 | Angela Rossini | Movie |
| It Started in Naples | 1960 | Lucia Curcio | Movie |
| The Millionairess | 1960 | Epifania | Movie |
| Two Women | 1960 | Cesira | Movie |
| That Kind of Woman | 1959 | Kay | Movie |
| Desire Under the Elms | 1958 | Anna, Wife-Ephraim's stepmother | Movie |
| Houseboat | 1958 | Cinzia Zaccardi | Movie |
| The Black Orchid | 1958 | Rose Bianco | Movie |
| The Key | 1958 | Stella | Movie |
| Boy on a Dolphin | 1957 | Phaedra | Movie |
| Ci troviamo in galleria | 1957 | Marisa | Movie |
| Legend of the Lost | 1957 | Dita | Movie |
| The Pride and the Passion | 1957 | Juana | Movie |
| Lucky to Be a Woman | 1955 | Antonietta Fallari | Movie |
| Scandal in Sorrento | 1955 | Sofia Cocozza – 'a Smargiassa' | Movie |
| Il segno di Venere | 1955 | Agnese Tirabassi | Movie |
| The Miller's Beautiful Wife | 1955 | Carmela | Movie |
| Attila | 1954 | Honoria | Movie |
| Un giorno in pretura | 1954 | Anna | Movie |
| Neapolitan Carousel | 1954 | Sisina | Movie |
| Poverty and Nobility | 1954 | Gemma | Movie |
| The Anatomy of Love | 1954 | La bella ragazza (segment “La macchina fotografica”) | Movie |
| The Gold of Naples | 1954 | Sofia (segment “Pizze a credito”) | Movie |
| The River Girl | 1954 | Nives Mongolini | Movie |
| Too Bad She's Bad | 1954 | Lina Stroppiani | Movie |
| Pilgrim of Love | 1954 | Beppina Delli Colli, Giulietta | Movie |
| The Country of the Campanelli | 1954 | Bonbon | Movie |
| Aida | 1953 | Aida | Movie |
| Two Nights with Cleopatra | 1953 | Cleopatra, Nisca | Movie |
| Africa sotto i mari | 1953 | Barbara Lama | Movie |
| La domenica della buona gente | 1953 | Ines | Movie |
| La tratta delle bianche | 1952 | Elvira (as Sofia Lazzaro) | Movie |
| La favorita | 1952 | Leonora (as Sofia Lazzaro) | Movie |
| Il sogno di Zorro | 1952 | Conchita (as Sofia Scicolone) | Movie |
| The Piano Tuner Has Arrived | 1952 | Amica di Giulietta (as Sofia Lazzaro) | Movie |
| Anna | 1951 | L'assistente di Vittorio al nightclub (uncredited) | Movie |
| Era lui… sì! sì! | 1951 | Odalisca (as Sofia Lazzaro) | Movie |
| Quo Vadis | 1951 | Lygia's Slave (uncredited) | Movie |
| Io sono il capataz | 1951 | Segretaria del Dittatore (as Sofia Scicolone) | Movie |
| Lebbra bianca | 1951 | A girl in the boardinghouse (as Sofia Lazzaro) | Movie |
| Il mago per forza | 1951 | La Sposa (as Sofia Scicolone) | Movie |
| Milano miliardaria | 1951 | Una commessa del bar (as Sofia Scicolone) | Movie |
| Il padrone del vapore | 1951 | Una ballerinetta (as Sofia Lazzaro) | Movie |
| Totò Tarzan | 1950 | Una tarzanide (uncredited) | Movie |
| Cuori sul mare | 1950 | Una ragazza al ristprante (as Sofia Scicolone) | Movie |
| Le sei mogli di Barbablù | 1950 | Ragazza rapita (as Sofia Lazzaro) | Movie |
| Il voto | 1950 | Un popolana alla festa di Piedigrotta (as Sofia Scicolone) | Movie |
| The Ed Sullivan Show | 1948 | Actress | TV Show |
